1st Leg (Petrarca Padova 10 Caerphilly 28)
Ceaphilly will defend an 18-point advantage as they bid to become only the third Welsh side to reach a European final.
Cardiff progressed to the 1996 Heineken Cup final, and last season, Pontypridd made it to the final of the PARKER PEN SHIELD.
Cearphilly will be without a number of key players for the match. Sione Tuipolutu, Joe El-Abd (both suspended) Holo Taufahema (leg) Sam Cox (shoulder), Richard Skuse (taken back by Bristol), Chris Ferris (knee ligaments) Luke Richards (ankle), Andrew Williams (AC joint) and El-Abd will all miss the crucial Padova match. But Faeo Vunipola (knee ligament), and Mark Workman (ankle) have both passed fitness tests and will start.
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Caerphilly:O Ashman; R Howells, R Boobyer, R Higgitt, G Lewis; J Thomas (capt), A Chiltern; L Manning, F Vunipola, D Sweet, D Davies, P Jones, G Jones, S Grainger, M Workman
Replacements; R Bilton, G Liddon, T Carless, N Rouse, N Watkins, F McLoughlin, J Murphy
Petrarca Padova: F Soler; F Faggiotto, M Bergamasco, R Salvan (capt), J Francesio; A Marcato, P Travagli; A Muraro, L Ferraro, M Matteralia, D Tumiati, G Llanos, E Bortolato, H Mazzocco, N Fitisemanu
Replacements; P Menapace, O Bortolusso, G Boccalon, R Rampazzo, F Dalla Nora, M Farsura, M Baroni