Captain Scott Gibbs has recovered from an ear-drum injury to take his place at inside centre, while budding Wales fullback Gavin Henson also gets the nod.
Samoan flyer Elvis Seveali’i has been preferred to Tongan Dave Tiueti at outside centre, while promising youngster Huw Bennett gets the nod over Barry Williams at hooker.
Of the starting lineup, only fly-half Shaun Connor and No 8 Nathan Bonner-Evans have yet to play Test rugby.
Ospreys: G Henson; S Terblanche, E Seveali’i, S Gibbs (capt), S Williams; S Connor, A Williams; D Jones, H Bennett, A Jones, A Newman, G Llewellyn, J Thomas, G Thomas, N Bonner-Evans.
Replacements: B Williams, A Millward, S Tandy, J Bater, A Durston, D Tiueti, G Morris.
