Colin Charvis is one of six Dragons injuries, Michael Owen is on Barbarians duty while James Harris and Gareth Chapman are on Wales Sevens duty. As a result, they will play no part in Friday evening’s dead rubber at Rodney Parade.
Gloucester’s Australian hooker Jeremy Paul returns from a hamstring strain. Props Jack Forster and Alasdair Dickinson, centre Ali James, stand-off Willie Walker and wingers James Bailey and Mark Foster make rare appearances.
This will be the first time that the two sides have met in a competitive match, with the Dragons looking to end a five-game losing run and extend their undefeated home record in the competition.
Dragons: Martyn Thomas; Richard Fussell, Rhodri Gomer Davies, Gareth Maule, Richard Mustoe; Ceri Sweeney (Capt), Andy Williams; Adam Black, Ben Daly, Gethin Robinson, Adam Jones, Peter Sidoli, Joe Bearman, Jamie Ringer, Nic Fitisemanu
Replacements: Steve Jones, Hugh Gustafson, Andrew Hall, Lewis Evans, Paul Emerick, Aled Thomas, Wayne Evans.
Gloucester: Olly Morgan; James Bailey, Leon Lloyd, Ali James, Mark Foster; Willie Walker, Mike Prendergast; Alasdair Dickinson, Jeremy Paul, Jack Forster; Will James, Marco Bortolami (Capt), Alasdair Strokosch, Andy Hazell, Gareth Delve
Replacements: Andy Titterrell, Christian Califano, Alex Brown, Luke Narraway, Gareth Cooper, Chris Paterson, James Simpson-Daniel