Halfpenny is the only change in the back division from the side that secured a first Premiership win in nine games against Newport.
In the pack, Gareth Gunter and Darren Fenton replace Rhys Gill and Scott Roberts at prop, Adam Whitney returns at flank, and Damian Welch continues in his new role on the other flank.
Cardiff:
Roger Davies
Leigh Halfpenny
Gareth Chapman
Tristan Davies (Capt)
Ryan Howells
Craig Evans
Darren Allinson
Gareth Gunter
Gary Horrigan
Darren Fenton
James Down
Chris Stamatakis
Damian Welch
Dan McShane
Adam Whitney
Replacements:
Rhys James
Richard Cornock
Scott Roberts
Gavin Lucas
Chris Jones
Luke Evans
Gareth Davies
