Williams who has been capped 44 times by Wales, and was part of the 2005 Grand Slam squad, hasn’t played for the Blues since suffering a dislocated knee cap playing against Glasgow Warriors last November.
The match gives a chance for many players to put their hands up for selection ahead of the Cardiff Blues big Heineken Cup matches in December.
Tickets for the friendly mach are available priced £1 for under 16’s and £5 for adults, and can be purchased on the night.
The Memorial Ground is located on Stirling Road, Ely, Cardiff.
Cardiff Blues 15 Rhys Williams 14 Gareth Thomas 13 Jamie Robinson 12 Dafydd Hewitt 11 Chris Czekaj 10 Ceri Sweeney 9 Richard Rees; 8 Mark Lewis 7 Ben White 6 Damion Welch 5 Scott Morgan 4 Deiniol Jones 3 Taufa’ao Filie 2 T Rhys Thoms 1 Scott Roberts
Substitutes: Gary Powell, Scott Andrews, Ross Johnson, Paul Tito, Bradley Davies, Darren Allinson, Nicky Robinson, Roger Davies, Ben Blair.