Italy, currently propping up the points table, have brought back wing Mirco Bergamasco along with halfbacks Fabio Semenzato and Kris Burton while experienced centre Gonzalo Canale also starts.
Up front Andrea Lo Cicero is fit again so starts at loosehead prop while Corne Van Zyl and Simone Favaro also come into the pack at second row and back row respectively.
Bergamasco is likely to take over the kicking duties as both Burton and Tobias Botes have wasted point scoring opportunites with wayward goalkicking.
ITALY:
15. Andrea Masi (Aironi Rugby)
14. Luke McLean (Benetton Treviso)
13. Gonzalo Canale (Clermont-Auvergne)
12. Alberto Sgarbi (Benetton Treviso)
11. Mirco Bergamasco (Racing-Metro Paris)
10. Kristopher Burton (Benetton Treviso)
9. Fabio Semenzato (Benetton Treviso)
1. Andrea Lo Cicero (Racing-Metro Paris)
2. Leonardo Ghiraldini (Benetton Treviso)
3. Lorenzo Cittadini (Benetton Treviso)
4. Quintin Geldenhuys (Aironi Rugby)
5. Cornelius Van Zyl (Benetton Treviso)
6. Alessandro Zanni (Benetton Treviso)
7. Simone Favaro (Aironi Rugby)
8. Sergio Parisse (Stade Francais)
Replacements:
16 Tommaso D’Apice (Aironi Rugby)
17 Fabio Staibano (Aironi Rugby)
18 Marco Bortolami (Aironi Rugby)
19 Robert Barbieri (Benetton Treviso)
20 Tobias Botes (Benetton Treviso)
21 Tommaso Benvenuti (Benetton Treviso)
22 Giulio Toniolatti (Aironi Rugby)