Sharpe steps down as captain after a distinguished career as one of the best locks in the game over the last 10 to 15 years.
And while he admits today’s game will be emotional, Sharpe is aiming to go out on a high.
“It’s an emotional day today, I think it’s something you can never prepare for fully,” he said.
“It’s been a tough season for us to get through and this is a big Test match.
“I don’t expect anything other than a hard game but if we execute our game plan, we will be in with a chance.”
Wales may have struggled so far this autumn but Sharpe believes Wales will respond.
“I think the thing is that teams who are in a tough time often show good character and we are expecting that from Wales tomorrow,” he added.
“I remember watching the 1999 World Cup at the Millennium Stadium but I’ve got plenty of good memories here and a couple of hard losses as well.”
With the Lions touring Australia next summer, Sharpe’s retirement means he won’t be available though he says he is leaving Australian rugby in good shape.
“There are a lot of guys who are experiencing their first northern hemisphere tours,” he commented.
“They are great tours and going on them is a great experience all round, you’ve got to enjoy that experience.
“I’ve been lucky enough to see these young guys come through and there is a lot of character within the group.
“I have seen guys develop this year and Australian rugby is going to be stronger for years to come as a result. I think our recent results are a good indication of that.”