There is just a six-day turnaround from opening their campaign with a 16-16 draw against Ireland at the Aviva last Sunday, recovering from 13-0 down.
Looking ahead to a first home fixture of the 2016 tournament, McBryde said:
“The biggest challenge for us after the short turnaround is to make sure there is plenty of energy in the group.
“Scotland are very canny bunch, they will come with plenty of trick plays in particular so they’ll have a few things up their sleeve.
“We’ve got to be aware of it, ready for it and fresh enough to deal with it through our recovery.”
Wales fly-half Dan Biggar limped off midway through the first-half last Sunday, with substitute Rhys Priestland prominent, both through goal-kicking and work in open play.
Such a performance means that whilst McBryde has promising initial news regarding the recovery of Biggar, the presence of Priestland means he is not overly concerned.
“Dan is out of the boot (cast) now, but we know there is not a lot of pressure on us to make that decision, because we have an able and experienced body in Rhys Priestland,” added McBryde.
“Everybody is aware of the strength’s Dan possess regarding his kicking game but Rhys is his own player and has his own abilities.
“You saw that on Sunday and ultimately Rhys is very comfortable playing that type of wide game in the channels.
“Rhys also proved that he is also as good as anyone under pressure kicking for points.”
Wales host Scotland on Saturday and, though they travel to England, also welcome France and Italy to the Principality Stadium during the remainder of the campaign.
Therefore McBryde also emphasised the importance of the making home turf a fortress in their 2016 RBS 6 Nations campaign, and the importance of clinical finishing.
“You want too win your home games and then try and pinch an away win so Saturday is important for us.
“It is important to get the balance right and we showed on the weekend that we are not that far away, we are creating plenty of opportunities it’s just about nailing them.
“We are looking at that one extra pass to try and be more ruthless.”
