Joe Thomas comes in at outside centre, with Harri Millard moving to inside centre. Reuben Morgan-Williams and Bryce Morgan get their first start at scrum half and lock respectively.
Wales beat Ireland 35-24 last Friday night, while Scotland beat England for the first time (24-6).
Strange said, “We are very pleased with our performance and result against Ireland. Scoring four tries away from home is a great platform to build on and we want to continue in that attacking vein this weekend.
“Scotland were excellent last weekend so we have no illusions about the task ahead. Although we have looked at Scotland’s game, it’s important we concentrate on our own performance.
“We are looking forward to returning to Eirias, we always have a fantastic welcome there and the crowd will no doubt give the players a boost.”
Adam Beard, Jarrod Evans and Owen Watkin have been called up by their Regions this weekend.
Strange added: “The players called up will benefit from regional rugby and it provides the opportunity for others to step up at this level. Five of our matchday squad are still qualified to play Under 18 rugby so this experience will stand them in good stead going forward. There is a huge amount of cooperation between coaches at the various age grades now so we know the development stage of the players available to us.”
Wales Under 20 v Scotland: Rhun Williams (RGC); Elis-Wyn Benham (Cardiff Blues), Joe Thomas (Ospreys), Harri Millard (Cardiff Blues), Keelan Giles (Ospreys); Dan Jones (Scarlets), Reuben Morgan-Williams (Ospreys); Corey Domachowski (Cardiff Blues), Dafydd Hughes (Scarlets), Dillon Lewis (Cardiff Blues), Shane Lewis-Hughes (Cardiff Blues), Bryce Morgan (Newport Gwent Dragons), Tom Phillips (captain, Scarlets), Shaun Evans (Scarlets), Harrison Keddie (Newport Gwent Dragons)
Replacements: Ifan Phillips (Scarlets), Robert Lewis (Cardiff Blues), Leon Brown (Newport Gwent Dragons), James Ratti (Ospreys), Morgan Sieniawski (Cardiff Blues), Declan Smith (Scarlets), Billy McBryde (Scarlets), Joe Gage (Ospreys)
Wales U20 home Six Nations tickets are available from:
Venue Cymru: www.venuecymru.co.uk, over the counter at their Llandudno box office or by calling the box office on 01492 872000.
WRU: www.wru.wales/tickets or by calling WRU ticket line on 0844 847 1881
Terrace tickets can also be bought from Colwyn Leisure Centre to personal callers or over the phone on 01492 577900. There is a £1 per ticket booking fee from all outlets
Wales Under Six Nations fixtures:
Ireland U20 24-35 Wales U20 Friday 5 February, Donnybrook
Wales U20 v Scotland Friday 12 February, Parc Eirias (6.30pm, S4C)
Wales U20 v France Saturday 27 February, Parc Eirias (7.45pm, S4C)
England U20 v Wales Friday 11 March Ashton Gate (7.45pm)
Wales U20 v Italy Friday 18 March, Parc Eirias (7.05pm, BBC Wales)