Ian Foster’s side are fully loaded for the clash at Principality Stadium which is their first in Europe as part of their northern hemisphere tour.
Barrett starts the game at fly-half with New Zealand captained by lock Sam Whitelock.
New Zealand are looking to maintain a winning run over Wales which dates back to 1953.
Barrett’s brother Jordie will be at full-back in a much-changed line-up from the side that hammered the United States 104-14 last weekend.
Brodie Retallick is back for his 90th cap to partner Whitelock who leads the visitors.
Props Joe Moody and Nepo Laulala join hooker Codie Taylor in also returning to the starting side.
“I can’t speak more highly about his contribution as a person to the black jersey,” All Blacks head coach Foster said of Beauden Barrett.
“It’s been three years since we played in Europe so there is a real sense of excitement.
“What better place to start than at a packed-out stadium here in Cardiff?
“The Welsh will play with their traditional passion and their fans singing in the stadium and they’ll throw everything at us.
“They are Six Nations champions and a very good team. They have a group of young players coming through who’ll be excited to play so we will have to be ready and we are.”
New Zealand: Jordie Barrett; Will Jordan, Anton Lienert-Brown, David Havili, Rieko Ioane; Beauden Barrett, TJ Perenara; Joe Moody, Codie Taylor, Nepo Laulala, Brodie Retallick, Samuel Whitelock (capt), Ethan Blackadder, Dalton Papalii, Ardie Savea
Replacements: Samisoni Taukei’aho, Karl Tu’inukuafe, Tyrel Lomax, Tupou Vaa’i, Akira Ioane, Brad Weber, Richie Mo’unga, Sevu Reece
Wales are Six Nations champions and a very good team. They have a group of young players coming through who’ll be excited to play so we will have to be ready and we are