It is all change in the Dragons front row, with Phil Price, Rhys Buckley and Dan Way getting an opportunity in place of Nathan Williams, Steve Jones and Nathan Buck against their Italian opposition.
The other changes from last weekend’s game against Perpignan come at half back where fit again Jason Tovey comes in for Matthew Jones and Joe Bedford replaces the rested Wayne Evans.
Full Back Jamie Smith is named on the bench having come through a couple of outings in the Principality Premiership after the hamstring and back injuries which have kept him out since the RaboDirect PRO12 match at Leinster in September.
Newport Gwent Dragons
Martyn Thomas, Will Harries, Adam Hughes, Andy Tuilagi, Aled Brew, Jason Tovey, Joe Bedford, Phil Price, Rhys Buckley, Dan Way, Adam Jones, Rob Sidoli, Danny Lydiate (c), Lewis Evans, Toby Faletau
Replacements:
Steve Jones, Nathan Williams, Nathan Buck, Sam Parry, Tom Brown, Jonathan Evans, Lewis Robling, Jamie Smith