The game is a repeat of last season’s final, which Cymoedd won 44-24 at the Principality Stadium. They also came out on top in the corresponding fixture, 12-8, and completed the treble with a 48-26 home win.
Cymoedd kicked-off the defence of their title with a 38-24 win over Gower College at Sardis Road last week. Coleg Sir Gar, meanwhile, started their Cup campaign with a 19-8 away win over Pembrokeshire College.
The other Cup matches see Gower College host Coleg Gwent, while there is an all-Blues battle in prospect between Cowbridge CS and Cardiff & Vale College.
In the Trophy tournament, Whitchurch HS return to the scene of their only triumph to date this season when they travel to Bridgend College. They beat them 44-6 in the qualification rounds.
Llandovery College play their first competitive game in the Trophy with a trip to Glantaf, while Neath & Port Talbot College travel to Parc Eirias, Colwyn Bay, to face Coleg Llandrillo.
WRU U18 DEVELOPMENT LEAGUE – Wednesday, 12 October
Cup
Coleg Sir Gar v Coleg y Cymoedd
Cowbridge CS v Cardiff & Vale College
Gower College v Coleg Gwent
Trophy
Bridgend College v Whitchurch HS
Coleg Llandrillo v Neath & P.Talbot College
Ysgol Glantaf v Llandovery College
TEAMS
Cup
Coleg Sir Gar v Coleg y Cymoedd
Coleg Sir Gar: Harri Doel; Ryan Conbeer, Joe Roberts, Scott Lloyd, Thomas Rogers; Llew Smith, Glenn Williams; Rhys Davies, Cameron Lewis, Llyr Green, Lewis Ellis–Jones (captain), Kingsley Jones, George David, Dan Davies, Gethin Davies
Reps: Drew Jones, Garan Williams, Adam Thomas, Steffan Richards, Callum Jenkins, Dafydd Llewelyn, Gino Setaro, Tom Lewis
Coleg y Cymoedd: Cole Swannack; Liam Lloyd, Rhys Davies, Eddie Francis, George Thomas; Cavan Slade, Nathan Griffiths; Declan Thomas, Iestyn Harris, Tom Stacey, Thomas John, Regan Wilton, Alun Lawrence (captain), Sion Edwards, Jack Perkins
Reps: Jamie Hill, Leon Davies, Connor Pavett, Ieuan Morris, Ben Warren, Tom Divine, Calun James, Ioan Davies
Gower College v Coleg Gwent
Gower College: Lewys Edwards; Jake Tucker, Ben Cambriani, Callum Carson, Brandon Wood; Corey Evans, Sam Cambriani (captain); Ollie Quick, Connor Edwards, Morgan Griffiths, Rhys Laugharne, Will Griffiths, Dan Pritchard, Evan Budge, Lloyd Dudley Jones
Reps: Rhys Thomas, Rhys Williams, Sam Hyde, Jack Fitzgerald, Max Jones, James Eynon
Coleg Gwent: Duane Thomas; Joel Whitcombe, Deon Smith, Cobi Edwards, David Trollope; Matthew Lewis (captain); Tom Bainton; Nathan Evans, Will Griffiths, Kayn Best, Llewi Maclean, Robert Brookson, Ben Pugh, Caelan May, Dan Sheppard
Reps: Declan Hill, Jack Gillard, Taylor Hanson, Jacob Hill, Cole Jones, Iwan Burgwin, Luke Shore, Jacob Lynch
Trophy
Bridgend College v Whitchurch HS
Bridgend College: Cam Fyffe-Davies; Garwyn Williams, Harri Morgan, Iwan Vasey, Ryan Morrin;Â Rhys Bridgeman, Callum Palmer; Cary Davies, Zach Taylor, Dewi Parrish, Steff Jones, Ryan Morgan, Euan Manley, Leon Evans, Brandon Huntley
Reps: Connor Buckle, Morgan Parsons, Louis Stansbury, Josh Richards, Brandon Mullen, Josh Evans, Jamie Hemming
Whitchurch HS: Will Young; Kane Teear-Bourge, Nat Ahmed, Toby Champ, Ruari O’Flynn; Conor Nagle, Morgan James; Joe Melhuish, Harry Boxall, Jack Sanders, Tom Simmister, Lewis Jameson, Owen Jones, Sion Parry (captain), Tom Rogers
Reps: Nathan Williams, Will Duingey, Tom Vanstone, Ashley Power, Max Harding, Evan Lloyd, Joshua Ions, Callum Jones, Harri Hill
Coleg Llandrillo v Neath & P.Talbot College
Coleg Llandrillo: Morgan Kirkham; Peter Jones, Rhys Henderson, Armani Roberts, Elis Roberts; Sam Rogers, Iago Davies; Patrick Maguire, Rhys Pomeroy, Shaun Thomas, Jake Bamber, Robin Williams, Liam Davies, Joseff Powell, Conor Hinchcliffe
Reps: Celt Lewis, Will Sanderson, Kieron Roberts, Dillon Edwards, Sol Ashley, Dylan Leach, Brayden Harding, Billy Alderson
Neath & P.Talbot College: TBC
Ysgol Glantaf v Llandovery College
Ysgol Glantaf: TBC
Llandovery College: Anson Lau; Elis Hudson, Tomi Lewis, Ty Jones, Sean Collins; Dan Wainwright, Aron Hemmings; Will le Bas, Ianto Jones (captain), Dan Davies, Max Richard, Olly White, Huw Richards-Price, Justin Muller, Dylan Jones
Reps: Cameron Evans, Olly Robb, Cian Ireland, Rhodri Bullock, Rhys Thomas
RESULTS TO DATE
Wednesday, 5 October
Cup
Coleg Gwent 29 – 13 Cowbridge CS
Pembrokeshire College 8 – 19 Coleg Sir Gar
Coleg y Cymoedd 38 – 24 Gower College
Trophy
Neath & P.Talbot College 62 – 0Â Bridgend College
Newport HS 55 – 15 Coleg Llandrillo
Whitchurch HS 13 – 22 Ysgol Glantaf