The young Welsh side crossed for six tries with wing Eleanor Hing, centre Hannah Bluck, Hannah Lane, who grabbed a brace of tries, centre Gabby Healan and lock Catrin Jones all getting on the scoresheet in a 34-22 victory.
This was the second of back-to-back league game against the Scottish side and the final game of this campaign and the Welsh side were well worth the win.
The victory made it three wins in this league campaign for Brython Thunder and saw them finish fourth in the Celtic Challenge table.
The Irish side, Wolfhounds, had already been crowned Celtic Challenge champions for a second successive season with their win over Edinburgh on Saturday.
The Thunder were looking to push for a fourth place finish ahead of kick-off with Edinburgh ahead of them on the table.
The home side opened the scoring with a well worked try after an opening period of pressure when wing Eleanor Hing crossed in the corner for the game’s first try.
There was a break in play with prop Cadi-Lois Davies was stretchered off with a leg injury but Brython settled the quickest with Wales centre Bluck crashing over from short-range fron a lineout.
Fly half Emma Marshall landed a magnificent touchline conversion to make it 12-0 after ten minutes to the Thunder.
Glasgow replied with their first try with their first real period of pressure by centre Nicole Flynn. Fellow centre Briar McNamara added the extras to make it 12-7.
Wing Ellie Tomans then nearly created one of the solo tries of the season, including two chip-kicks, but full-back Hannah Lane did cross in the corner for her second try of the season.
Centre Gabby Healan then took advantage Thunder’s expansive approach and ran in for a 60m solo try to score under the posts. Marshall added the conversion to make it 24-7.
Glasgow crossed for their second try by wing Emily Norval in the corner to claw the Scots back into the contest before prop Poppy Fletcher crossed for a third try to make it 24-17 at half-time.
After the break, lock Catrin Jones crashed over for the Welsh side’s fifth try to extend the home side’s lead.
Glasgow replied almost straight away with a try by Orla Proctor to make it a seven-game midway through the second half.
But it was full back Lane that sealed the win after a superb counter-attack in the dying moments to clinch a impressive victory for Brython.
