The English champions return to the home of English football and lock horns with a new-look Ospreys side, which will be looking to get their campaign back in track after 26-all draw to Treviso in Italy.
Saracens will be hoping to do better than the last time they ran out at Wembley in the English capital when they lost 25-23 to reigning champions Leinster in last season’s Heineken Cup.
The Ospreys, who failed to reach the quarter-finals of the tournament for the first time in three years last season, don’t have a great away record in Europe and have not won in six games on the road.
The Premiership outfit, who returned to top flight European action for the first time in three years last season, like the Ospreys in the Pro12, lie in second place in their domestic league.
