The Welsh region will be looking to avenge their 31-26 defeat to Saracens at Wembley last weekend when the two sides clash in Swansea in the return game of their double header.
The Ospreys know the visit of the side from the English capital is a ‘must-win’ game if they have genuine ambitions to reach the knockout stages of European rugby’s premier competition.
Saracens top the Pool but only four points separate all four teams after three games in the tightest fought group in this season’s tournament. The Premiership outfit know a victory in Wales will be a major boost of their quarter-finals hopes.
The English side, who are in their fifth season in the Heineken Cup, has lost their last four Heineken Cup games on the road and will be no illusions of the task facing them in the Principality.