Wales second row Luke Charteris could be set to make his 100th RaboDirect PRO12 appearance if he comes onto the pitch to face Treviso.
At the other end of the spectrum, 17-year-old full back Hallam Amos is named in the squad having recently returned from the FIRA U18s European Championship where Wales finished in 4th place.
Hallam put in a number of impressive performances during the tournament and could be set to make his first appearance for the senior Dragons side at Rodney Parade. He has made one previous appearance for the Dragons, making his debut in the LV= Cup pool game at Wasps earlier in the season.
Andy Tuilagi misses out on a place in the squad with a dead leg and fly half Steffan Jones is ruled out because of an ankle injury picked up in Cross Keys’ British & Irish Cup semi-final win over Cornish Pirates.
Scott Morgan is named in the squad for the first time since recovering from a pectoral injury.
Newport Gwent Dragons Squad
Martyn Thomas, Will Harries, Hallam Amos, Tonderai Chavhanga, Aled Brew, Adam Hughes, Ashley Smith, Lewis Robling, Jason Tovey, Joe Bedford, Wayne Evans, Tom Brown, Toby Faletau, Dan Lydaite, Lewis Evans, Andrew Coombs, Luke Charteris, Scott Morgan, Rob Sidoli, Dan Way, Nathan Buck, Nathan Williams, Phil Price, Steve Jones, Sam Parry, Hugh Gustafson.